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Articles
Calculating variant penetrance from family history of disease and average family size in population-scale data
Genetic penetrance is the probability of a phenotype when harbouring a particular pathogenic variant. Accurate penetrance estimates are important across biomedical fields including genetic counselling, disease
Authors: Thomas P. Spargo, Sarah Opie-Martin, Harry Bowles, Cathryn M. Lewis, Alfredo Iacoangeli and Ammar Al-Chalabi
Citation:Genome Medicine
Content type: MethodPublished on: 15 December
Multi-region sequencing with spatial information enables accurate heterogeneity estimation and risk stratification in liver cancer
Numerous studies have used multi-region sampling approaches to characterize intra-tumor heterogeneity (ITH) in hepatocellular carcinoma (HCC). However, conventional multi-region sampling strategies do not pres
Authors: Chen Yang, Senquan Zhang, Zhuoan Cheng, Zhicheng Liu, Linmeng Zhang, Kai Jiang, Haigang Geng, Ruolan Qian, Jun Wang, Xiaowen Huang, Mo Chen, Zhe Li, Wenxin Qin, Qiang Xia, Xiaonan Kang, Cun Wang…
Citation:Genome Medicine
Content type: ResearchPublished on: 16 December
Spatiotemporal evolution of the clear cell renal cell carcinoma microenvironment links intra-tumoral heterogeneity to immune escape
Intratumoral heterogeneity (ITH) is a hallmark of clear cell renal cell carcinoma (ccRCC) that reflects the trajectory of evolution and influences clinical prognosis. Here, we seek to elucidate how ITH and tum
Authors: Mahdi Golkaram, Fengshen Kuo, Sounak Gupta, Maria I. Carlo, Michael L. Salmans, Raakhee Vijayaraghavan, Cerise Tang, Vlad Makarov, Phillip Rappold, Kyle A. Blum, Chen Zhao, Rami Mehio, Shile Zhang, Jim Godsey, Traci Pawlowski, Renzo G. DiNatale…
Citation:Genome Medicine
Content type: ResearchPublished on: 19 December
Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-c Fernando botero brief biography of martin
We may earn commission from links on this page, but we only recommend products we back. Famed Colombian sculptor and painter Fernando Botero died September 15 of pneumonia complications, according to the Associated Press.
Summit bhardwaj biography of martin
Sumit Bhardwaj was born on in Delhi, India. He made his acting debut with Raj Purohit's Bollywood film Sixteen in Sumit Bhardwaj hails from Delhi, India.
Fabiola shyne biography of albert einstein
Einstein also made important contributions to quantum mechanics. Born in the German EmpireEinstein moved to Switzerland inforsaking his German citizenship the following year.
El capo de capos pablo escobar biography
Explore the life of Pablo Escobar, from his humble beginnings to becoming a notorious drug lord, and the effects on his family. Escobar emerged from a humble background, raised in poverty as the son of a schoolteacher and a farmer.
Biography on joan of arc life story
Stamps were low-priced and could be pasted in a booklet that when filled was traded for a war bond. Michael, Catherine, and Margaret that inspired her.
Harry anderson biography night court episode
Harry Laverne Anderson October 14, - April 16, was an American actor, comedian and magician. In addition to eight appearances on Saturday Night Live between andAnderson had a recurring guest role as con man Harry "The Hat" Gittes on Cheers - He played Richie Tozier in the miniseries Itbased on the Stephen King novel of the same name.
Fernando botero brief biography of martin
We may earn commission from links on this page, but we only recommend products we back. Famed Colombian sculptor and painter Fernando Botero died September 15 of pneumonia complications, according to the Associated Press.
Summit bhardwaj biography of martin
Sumit Bhardwaj was born on in Delhi, India. He made his acting debut with Raj Purohit's Bollywood film Sixteen in Sumit Bhardwaj hails from Delhi, India.
Fabiola shyne biography of albert einstein
Einstein also made important contributions to quantum mechanics. Born in the German EmpireEinstein moved to Switzerland inforsaking his German citizenship the following year.
El capo de capos pablo escobar biography
Explore the life of Pablo Escobar, from his humble beginnings to becoming a notorious drug lord, and the effects on his family. Escobar emerged from a humble background, raised in poverty as the son of a schoolteacher and a farmer.
Biography on joan of arc life story
Stamps were low-priced and could be pasted in a booklet that when filled was traded for a war bond. Michael, Catherine, and Margaret that inspired her.
Harry anderson biography night court episode
Harry Laverne Anderson October 14, - April 16, was an American actor, comedian and magician. In addition to eight appearances on Saturday Night Live between andAnderson had a recurring guest role as con man Harry "The Hat" Gittes on Cheers - He played Richie Tozier in the miniseries Itbased on the Stephen King novel of the same name.
Zhou Enlai
Premier of China from to
In this Chinese name, the family name is Zhou.
Zhou Enlai (Chinese: 周恩来; pinyin: Zhōu Ēnlái; Wade–Giles: Chou Ên-lai; 5 March 8 January ) was a Chinese statesman, diplomat, and revolutionary who served as the inaugural premier of the People's Republic of China (PRC) from until his death in , and concurrently as the inaugural Minister of Foreign Affairs from to Zhou was a key figure in the Chinese Communist Party (CCP) and ally of Mao Zedong during the Chinese Civil War, later helping consolidate its control, form its foreign policy, and develop the economy.
Born in Jiangsu, as a student Zhou was involved in the May Fourth Movement, and in the early s studied in France, where he joined the newly-founded CCP. During the party's alliance with the Kuomintang (KMT), he worked in the political department of the Whampoa Military Academy. In , Zhou led the worker uprising which was crushed by the KMT in the Shanghai massacre, after which he helped lead the Nanchang uprising. Zhou worked underground in Shanghai before being transferred to the Jiangxi Soviet, and after the soviet's defeat was a member of the party's top leadership during its Long March. Zhou came to support Mao Zedong, who became leader of the CCP in During the Xi'an Incident in , Zhou successfully persuaded KMT leader Chiang Kai-shek to agree to form a Second United Front against the Japanese. During the Second Sino-Japanese War, Zhou was the resident representative of the CCP in Chongqing, and during the renewed civil war from assisted Mao in commanding military campaigns.
After the establishment of the PRC in , Zhou was appointed head of government and foreign minister. Advocating peaceful coexistence with the West after the Korean War, he participated in the Geneva Conference and Bandung Conference and helped orchestrate Richard Nixon's visit to China. He helped devise policies regarding disputes with the United State .